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Oxazepam , as with other benzodiazepine drugs, may cause tolerance, physical dependence, addiction and benzodiazepine withdrawal syndrome. Withdrawal from oxazepam or other benzodiazepines often leads to withdrawal symptoms similar to those seen with alcohol and barbiturate withdrawal. The higher the dose and the longer the drug is taken, the greater the risk of unpleasant withdrawal symptoms. Withdrawal symptoms, however, may occur at standard dosages and even after short-term use. Treatment with benzodiazepines should be discontinued as soon as possible through a slow and gradual dose reduction plan. Buy sobril 25 mg in sweden
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It is an intermediate-acting benzodiazepine with a slow action, so it is usually prescribed to individuals who have difficulty sleeping, rather than falling asleep. It is usually prescribed for anxiety disorders with associated tension, irritability and agitation. It is also prescribed for drug and alcohol use and for anxiety associated with depression. Doctors can use oxazepam outside of its approved indications to treat social phobia, post-traumatic stress disorder, insomnia, premenstrual syndrome and other conditions.
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Because oxazepam is an active metabolite of diazepam, an overlap in possible interactions with other drugs or foods is likely, with the exception of the pharmacokinetic CYP450 interactions (eg with cimetidine). Precautions and following the prescription are required when taking oxazepam (or other benzodiazepines) in combination with antidepressant drugs (SSRIs such as fluoxetine, sertraline and paroxetine, or several reuptake inhibitors such as bupropion, duloxetine or venlafaxine), potent painkillers (opioids), morphine, oxycodone or methadone). Concomitant use of these drugs (as well as other benzodiazepines) may interact in a way that is difficult to predict. Drinking alcohol while taking oxazepam is not recommended. Concomitant use of oxazepam and alcohol may lead to increased sedation, severe problems with coordination (ataxia), decreased muscle tone and in severe cases or in predisposed patients, even to life-threatening poisonings with respiratory depression, coma and collapse. There is a risk of blood circulation collapsing, perhaps the same condition as the blood circulation syncope, when oxazepam is used in combination with quetiapine, an antipsychotic.